Webb1 mars 2012 · Thymopoiesis is a complex process involving cross-talk between developing thymocytes and the nonhematopoietic supporting stromal microenvironment, which comprises specialized thymic epithelial cells (TECs), endothelium, fibroblasts, and dendritic cells (DCs) ( 4, 5 ). WebbFör 1 dag sedan · Objectives No consensus was reached on the efficacy of postoperative radiotherapy (PORT) in locally invasive thymomas because of the rarity of the thymic epithelial and the variations of study results. Therefore, we aimed to explore the efficacy of PORT in locally invasive thymomas using the Surveillance, Epidemiology, and End …
A case of mediastinal mesenchymal tumor with pericytic …
Webb1 juni 2003 · Thymic microenvironment Bone marrow Host environment Fractionated whole-body irradiation Introduction 3 Thymic lymphoma induced by fractionated whole-body irradiation (FWI) was first described by Kaplan et al. (1953) and has been used as a mode to study the mechanism of radiation carcinogenesis. WebbIL-22–deficient mice. IL-22, which signaled through thymic epithelial cells and promoted their proliferation and survival, was up-regulated by radio-resistant RORg(t)+CCR6+NKp46– lymphoid tissue inducer cells after thymic injury in an IL-23–dependent manner. Administration of IL-22 enhanced thymic recovery after total body irradiation. psicologa thatiane vieira
The Role of the Thymus in Immune Reconstitution in Aging, Bone …
Webb5 apr. 2024 · It is proposed that acute irradiation persistently disturbs the heterogeneity and properties of mTECs, and may thereby impair TSA expression for thymic T cell selection. The thymus has the ability to regenerate from acute injury caused by radiation, infection, and stressors. In addition to thymocytes, thymic epithelial cells in the medulla … WebbNoxa loss enhances γ-radiation-induced thymic lymphoma development. Notably, after fractionated γ-irradiation, noxa −/− mice developed thymic lymphoma with markedly higher incidence and accelerated rate compared with wild-type mice (median survival: 126 d for noxa −/− vs. 217 d for wild type; P < 0.0005) ().There was even a trend toward … Webb25 mars 2024 · In the mediastinum, mesenchymal tumor is rare, whereas thymic tumor, cystic disease, and neurogenic tumor are common. ... resection after radiotherapy could be difficult because tissue scarring might occur due to inflammation caused by irradiation. 13 We considered the occurring risk of postoperative complication would be high, ... psicologas forocoches