Thr 308
WebJan 25, 2008 · Akt is a protein serine/threonine kinase that is involved in the regulation of diverse cellular processes. Phosphorylation of Akt at regulatory residues Thr-308 and Ser … Webp-Akt1 Antibody (Thr 308) has been replaced by a more specific monoclonal antibody, p-Akt1/2/3 (B-5) that gives a stronger signal & more reproducible data.
Thr 308
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WebMar 4, 2024 · After transfected AKT constructs with various mutants where either or both of Ser473 and Thr 308 were mutated to alanine to prevent AKT from activation in HEK293T … WebJun 25, 2009 · Akt activation is controlled by phosphorylation at 2 different sites, Thr 308 and Ser 473. 38,39 We have recently reported that highly differentiated CD8 + CD28 − …
WebPhosphorylation on Thr-308, Ser-473 and Tyr-474 is required for full activity. Activated TNK2 phosphorylates it on Tyr-176 resulting in its binding to the anionic plasma membrane … Webphosphorylation at Thr-308 to regulate cell proliferation and survival. Akt/protein kinase B (PKB),2 also named RAC kinase, is involved in the regulation of diverse cellular processes, …
WebJul 6, 2024 · However, our results establish that the phosphorylation state of Thr-308 is a superior readout for the activation state of Akt. Whereas phosphorylation at Thr-308 alone is able to activate Akt1, phosphorylation of Ser-473 alone leads to relatively weak activity in vitro and no detectable activity in the cell. WebPhospho-AKT1 (Thr308) Antibody (44-602G) in IHC (P) Immunohistochemistry analysis of AKT/PKB (pT308) showing staining in the cytoplasm and nucleus of paraffin-embedded …
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