NettetIntranasal administration is a non-invasive route for drug delivery, which is widely used for the local treatment of rhinitis or nasal polyposis. Since drugs can be absorbed into the systemic circulation through the nasal mucosa, this route may also be used in a range of acute or chronic conditions … NettetThe injection volume recommended as the maximum volume per neonatal mouse or rat is 100 µL, and that for weanling or older mice is up to 300 µL. To inject into the cerebral …
Immunomodulative Effects of Chamaecyparis obtusa Essential Oil in Mouse …
Nettet10. jun. 2024 · A CVST model was induced by ferric chloride in male C57BL/6J mice. The selective cGAS inhibitor RU.521, STING agonist 2′3′-cGAMP, and STING siRNA were delivered by intranasal administration or intraventricular injection. Nettet1. mar. 2024 · Both administration routes showed a dose-dependent increase in total BAL cells (Fig. 3 A).A significant higher number of total BAL cells was observed in the IMIT mice treated with either vehicle (p < 0.05) or 1 μg/ml LPS (p < 0.01) compared to mice administered using OA.For the highest concentration of LPS, 100 μg/ml, no significant … crystal isles difficulty offset
Intratracheal administration of solutions in mice; development and ...
NettetI dag · Intranasal administration of the vaccine induced higher serum anti-spike antibody titers in HLA-DQ6 (NOD) mice than in Balb/c mice, with evidence of a dose dependent response in both strains. Intranasal administration of Ad5-RBD produced marginally higher serum anti-spike IgG titers in comparison to intramuscular administration in HLA … Nettet18. aug. 2024 · The present study aims to investigate the immunomodulatory effects of essential oil from Chamaecyparis obtusa (EOCO) in an ovalbumin (OVA)-induced allergic rhinitis (AR) mouse model. BALB/c mice were intraperitoneally sensitized and stimulated with OVA. From day 22 to 35, 0.01% and 0.1% ECOC was intranasally administered 1 … NettetTable 1. Recommended maximum volumes and their relative targets from intranasal delivery of substances to mice and rats . Being a larger animals, rats may tolerate … dwight feanny westat