Web13. dec 2024. · Bladder Urothelial Carcinoma (BLCA) is the major subtype of bladder cancer, and the prognosis prediction of BLCA is difficult. Ferroptosis is a newly discovered iron-dependent cell death pathway. However, the clinical value of ferroptosis-related genes (FRGs) on the prediction of BLCA prognosis is still uncertain. In this study, we aimed to … WebRT @FrontOncology: New research: Upregulation of the ferroptosis-related STEAP3 gene is a specific predictor of poor triple-negative breast cancer patient outcomes ...
Identification of a key ceRNA network associated with ferroptosis …
Web12. feb 2024. · Ferroptosis is an intracellular iron-dependent form of cell death that is distinct from apoptosis, necrosis, and autophagy. Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy. The development of resistance to cancer therapy remains a major challenge. A … Web25. maj 2012. · Ferroptosis cannot be explained by a simple increase in H 2 O 2-dependent, iron-catalyzed ROS production (i.e., Fenton chemistry), as H 2 O 2-induced death is distinct from RSL-induced ferroptosis (Figures 1 and 2). Rather, our results are most consistent with one or more iron-dependent enzymes functioning as part of the core … gazala order of battle
El Niño Alex on Twitter: "RT @FrontOncology: New research: …
Web23. maj 2024. · Ferroptosis is an iron-dependent regulated cell death characterized by lipid peroxidation and iron overload, which is different from other types of programmed cell death, including apoptosis, necroptosis, autophagy, and pyroptosis. Over the past years, emerging studies have shown a close relation between ferroptosis and various cardiovascular … Web22. dec 2024. · In addition, MAPK3 acts as a driver and CD44 acts as a suppressor in the FerrDb. These results suggest an essential role for MAPK3 and CD44 in ferroptosis. The results of GSEA enrichment analysis showed that MAPK3 was significantly positively correlated with several pathways, including “ferroptosis” and “acute myeloid leukemia”. Web29. jul 2024. · The networ k of interactions among these ge nes showe d tha t MAPK3, N QO1, CDKN2A, TXN, and othe r gene s ... Ferroptosis expression profiles, the … gazal gas heater