Glycol ingestion

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August undefined, 2024

WebJul 9, 2024 · Methanol and ethylene glycol poisonings cause scores of fatal intoxications annually, and even relatively small ingestions of these alcohols can produce significant … WebAug 1, 2011 · The advent of this modified enzymatic assay goes a long way in enhancing the role of the laboratory in the management of the life-threatening condition, ethylene glycol poisoning. The assay needs to be embraced by laboratorians to confirm its validity in identifying this serious form of intoxication, which constituted 2% of poisonings …

A Case of Chronic Ethylene Glycol Intoxication Presenting without ...

WebEthylene glycol ingestion results initially in CNS effects. After a characteristic latent period, signs of inebriation may be followed by serious illness, and even death, caused by toxic metabolites.. Propylene glycol, which is much less toxic than ethylene glycol, is metabolized to compounds that are normal constituents of the citric acid cycle.. No … WebPropylene glycol toxicity has not been well studied. The incidence of toxic effects, predisposing factors, and dose–effect relations are not known. Case reports have described hyperosmolality, with or without lactic acidosis, in patients in whom propylene glycol was used as a vehicle to deliver topical silver sulfadiazene cream,1,3 ... pilot light food education center

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Web1 day ago · Triethylene Glycol (TEG) is a colorless, odorless, and hygroscopic liquid with low toxicity. It is primarily used as a solvent, particularly in the production of plastics, … Webglycol, any of a class of organic compounds belonging to the alcohol family; in the molecule of a glycol, two hydroxyl (―OH) groups are attached to different carbon atoms. The … WebEthylene glycol toxicity is categorized into three broad overlapping stages of adverse health effects. Stage 1 (the neurological stage) lasts from 30 minutes to 12 hours after ingestion. Stage 2 (the cardiopulmonary stage) occurs between 12 and 24 hours after ingestion. Stage 3 (the renal stage) occurs between 24 and 72 hours after ingestion. pilot light floor furnace

Toxic Alcohols NEJM

WebEthylene glycol poisoning is a relatively common occurrence worldwide. Thousands of cases of poisoning and some fatal cases occur annually in the United States alone (AAPCC 2016). Systemic ethylene glycol … WebEthylene glycol toxicity is characterized by an osmolal gap and metabolic acidosis with an elevated anion gap. Nephrotoxicity after ethylene glycol ingestion typically occurs 24 … pilot light for gas furnaceWebBackground: We describe a case of acute propylene glycol toxicity following ingestion of ethanol and propylene glycol-containing antifreeze in which blood lactate, serum … pings house

"WebJul 29, 2024 · Methanol and ethylene glycol poisonings cause scores of fatal intoxications annually, and even relatively small ingestions of these alcohols can produce significant toxicity. Rapid recognition and early treatment, including alcohol dehydrogenase (ADH) … " - Glycol ingestion

Glycol ingestion

Laboratory Diagnosis of Ethylene Glycol Poisoning American …

WebOct 1, 2014 · Propylene glycol (PG) is a commonly used solvent for oral, intravenous, and topical pharmaceutical agents. Although PG is generally considered safe, when used in high doses or for prolonged periods, PG toxicity can occur. Reported adverse effects from PG include central nervous system (CNS) toxicity, hyperosmolarity, hemolysis, cardiac …

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WebJun 26, 2014 · Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and without the classic metabolic derangements. WebEthylene glycol poisoning is a relatively common occurrence worldwide. Thousands of cases of poisoning and some fatal cases occur annually in the United States alone (AAPCC 2016). Systemic ethylene glycol …

WebNov 28, 2024 · Ethylene glycol is one of several toxic alcohols that have medical and toxicological importance; the other principal ones are methanol and isopropanol (see Alcohol Toxicity ). If untreated, ingestion of ethylene glycol can be fatal. Ethylene glycol is the major ingredient of almost all radiator fluid products in the United States. WebKey Points. Accidental or intentional ingestion of antifreeze is the most common route of exposure leading to ethylene glycol toxicity, resulting in thousands of poisonings reported each year in the United States. Inhalation of ambient air, ingestion of drinking water, or skin contact with water or soil are not expected to be significant routes ...

WebSep 26, 2024 · National Center for Biotechnology Information WebTripropylene Glycol Monomethyl Ether, commonly known as TPM, is a clear, colorless liquid that belongs to the glycol ether family. It is characterized by its low toxicity, low odor, and excellent solvency properties. This versatile solvent is miscible with both water and a wide range of organic solvents, making it a valuable component in many ...

WebPropylene glycol is a colorless, nearly odorless, thick liquid. It has a variety of uses beyond being a food additive. It's used in many products because it helps them maintain their …

WebJun 19, 1997 · Her blood ethylene glycol concentration was 390 mg/L, and she was treated with an intravenous ethanol infusion and hemodialysis. During the tenth and eleventh day after admission bilateral seventh cranial nerve paralysis developed, as well as bilateral dysfunction of cranial nerves II, V, VIII, IX, X, and XII. pilot light for electric water heaterThe three main systems affected by ethylene glycol poisoning are the central nervous system, metabolic processes, and the kidneys. The central nervous system is affected early in the course of poisoning as the result of a direct action of ethylene glycol. Similar to ethanol, it causes intoxication, followed by drowsiness or coma. Seizures may occur due to a direct effect. The toxic mechanism of ethylene glycol poisoning is mainly due to the metabolites of ethylene glycol. Initi… pings ichiban venice flWebEthylene glycol is a component of antifreeze and engine coolant, and its ingestion is much less common than ethanol intoxication. Poison control centers have reported between 4000 and 6000 cases of ethylene glycol exposures per year. 1 Nonspecific symptoms such as depressed mental status with ingestion of either substance may lead providers to ... pings house upton menuWebFeb 20, 2024 · nausea. vomiting. As your body continues to break down the antifreeze over the next several hours, the chemical can interfere with your kidney, lung, brain, and nervous system function. Organ ... pilot light foundationWebApr 16, 2001 · The propylene glycol ethers (PGEs), even at much higher exposure levels, do not cause the types of toxicity produced by certain of the ethylene glycol ethers (EGEs). Specifically, they do not cause damage to the thymus, testes, kidneys, blood, and blood-forming tissues as seen with ethylene glycol methyl and ethyl ethers. pilot light for gas hot water heaterWebDiethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. It is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste. It is a four carbon dimer of ethylene glycol.It is miscible in water, alcohol, ether, acetone, and ethylene glycol. DEG is a widely used solvent. It can be a contaminant in consumer products; this … pings hoursWebNov 28, 2024 · The classic laboratory profile of ethylene glycol ingestion is an early osmolar gap (the ethylene glycol serves as an unmeasured osmole) that disappears as … pings in lost ark