WebOct 16, 2015 · Tan sheep exhibited the smallest body size with 61.54 ± 6.42 (P < 1.0*10 −7, Fig. 1b ). We randomly selected two female sheep each from UQ, Tan, StH and Hu, along with two male sheep from UQ in ... WebJul 15, 2024 · The expression of SMAD1 was measured by western blotting. C. The binding of USP9X and SMAD1 protein was detected by co-immunoprecipitation. D. Activated HSCs were treated with CHX for 0, 2 or 4 h. CHX-treated HSCs were then transfected with siNC or siUSP9X. The binding of USP9X and SMAD1 protein was detected by western blotting.
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WebSep 13, 2013 · The TGF-β1/ALK5/Smad3 signaling pathway has been studied in fibrosis extensively. However, an increasing number of studies involving the ALK1/Smad1 pathway in the fibrotic process exist. In this ... WebSMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. … nily farm
RUNX1 regulates SMAD1 by transcriptionally activating
WebOct 1, 2012 · We found a positive correlation between activation of Smad1/5/8 and inhibition of DNA synthesis. ... anti-Smad1 was from Upstate (Millipore, MA, USA) and CST, anti-2A was from Millipore, anti-actin was from Santa Cruz Biotechnology (CA, USA) and anti-PGK1 was from Abcam. Anti-BMP-7 (clone M1-F8) was from AbD Serotec. Antibodies used for … WebMar 8, 2024 · It is predicted that miR-182-5p may bind to the 3’UTR regions of SMAD1, SMAD3 and SMAD4 . After transfected with miR-182-5p mimics, we found that it could significantly increase the expression of miR-182-5p in HFs . So Western Blot was arranged to further detect the effect of miR-182-5p overexpression on the expression of SMADs. WebThe ALK-1/Smad1 pathway in cardiovascular physiopathology. A new target for therapy? Activin receptor-like kinase-1 or ALK-1 is a type I cell surface receptor for the … nily peters