Cst hif-1α
WebRegulation of HIF-1α stability can also be mediated by an oxygen-independent pathway. In the cytoplasm, HIF-1α is bound to heat-shock protein 90 (Hsp90), leading to enhanced HIF-1α stability. Displacement if … Webof HIF-1α protein synthesis. Conclusion— These results show that KC7F2 is a potent HIF-1 pathway inhibitor and that its potential as a cancer therapy agent warrants further study.
Cst hif-1α
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WebJun 21, 2024 · C RT-PCR detection of HIF-1α (FL) and HIF-1α (Del) showing fragments of 576 and 235 bp for HIF-1α FL and HIF-1α, respectively. The panel inside indicates the design strategy of primers. WebThe HIF-1α Translation Inhibitor, KC7F2, also referenced under CAS 927822-86-4, controls the biological activity of HIF-1α. This small molecule/inhibitor is primarily used for Cell Structure applications. Expand. Hide. Match Criteria: Product Name, Keyword. All Photos (3) Anti-HIF1A antibody produced in rabbit. Compare
WebCUT&RUN was performed with MCF7 cells treated with cobalt chloride (100 μM) overnight and HIF-1α (D2U3T) Rabbit mAb or Rabbit (DA1E) mAb …
WebOct 9, 2007 · Abstract. Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix-PAS domain transcription factor that is expressed in all metazoan organisms and is composed of HIF-1α and HIF-1β subunits. Under hypoxic conditions, HIF-1 regulates the transcription of hundreds of genes in a cell type–specific manner. The HIF-1α subunit is regulated ... WebHighly specific and rigorously validated in-house, HIF-1α Antibody (CST #3716) is ready to ship. ... 在常氧条件下，HIF-1α 会发生脯氨酸羟基化， …
WebJun 1, 2024 · Antibodies used were as follows: UCHL1 (CST#13179), Hif-1α（GeneTex #GTX127309），GAPDH (CST #5174 S), Ubiquitin (sc-8017). 2.4. Immunoprecipitation assay. ... HIF-1α is a potential target of UCHL1 after myocardial infarction (MI). (A) Schematic representation of UCHL1 proximity-labeling by BioID. In the presence of …
WebJun 21, 2024 · Hypoxia-inducible factor 1α (HIF-1α) plays pivotal roles in maintaining pluripotency, and the developmental potential of pluripotent stem cells (PSCs). However, … northgate polyclinic primary careWebMay 1, 2024 · However, silencing of HIF-1α by siRNAs abolished this Foxo1 expression upregulation. Meanwhile, the stabilization of HIF-1α at protein level by DMOG can also induce the accumulation of Foxo1 in β cells. Importantly, the upregulation of Foxo1 expression by CoCl2 or by DMOG was further confirmed in primary human β cells. northgate post officeWebMar 21, 2024 · This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. ... Monoclonal Antibody - 200-301-F45 and Anti-Hif-1α hydroxy P564 (RABBIT) Antibody - 100-401-A25; Abcam antibodies for HIF1A. HIF-1 alpha; Buy Protein products … northgate portsmouthWeb人髓过氧化物酶(MPO)ELISA试剂盒HIF-1 Alpha 缺氧诱导因子1α 抗体HIF-1α Human trypsinogen activation peptide,TAP ELISA HIF-1β/ARNT1 缺氧诱导因子1β 抗体 Human Trypsinogen-2,Try-ⅡELISA HIF 2α 缺氧诱导因子2α 抗体HIF-2α human tryptophanyl-tRNA synthetase,WARS ELISA how to say diphtheriaWebApr 8, 2024 · Myocardial infarction (MI) is a fatal heart disease that affects millions of lives worldwide each year. This study investigated the roles of HIF-1α/lncRNA-TUG1 in mitochondrial dysfunction and pyroptosis in MI. CCK-8, DHE, lactate dehydrogenase (LDH) assays, and JC-1 staining were performed to measu … how to say dirty dishes in spanishWebAug 27, 2024 · Cardamonin, a chalcone isolated from Alpiniae katsumadai, has anti-inflammatory and anti-tumor activities. However, the molecular mechanism by which cardamonin inhibits breast cancer progression largely remains to be determined. CCK-8 and Hoechst 33258 staining were used to detect cell growth and apoptosis, respectively. HIF … northgate pond chesterWebHypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor that plays a critical role in the cellular response to hypoxia (1). The HIF1 … northgate post office phone number