WebEnpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 exhibits selective antiproliferative activity for cancer cells. WebJul 7, 2014 · DLD-1 cells were provided by the National Cancer Institute (part of the NCI-60 collection). All cell lines were thawed immediately prior to experimentation, and cell lines are characterized by NCI using short tandem repeat profiling. The cisplatin stock solution used for culturing CP.5 cells were prepared in PBS.
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WebAnti-cancer Compound Library ... In U2OS cancer cell line, BMH-21 results in degradation of RPA194 and translocation of NCL with IC50 of 0.05 μM and 0.07 μM, respectively. ... * When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online). The Serial ... WebJan 1, 2014 · Compounds. Stock solutions of all compounds were prepared in dimethylsulfoxide ... To test this hypothesis we treated pancreatic cancer cells with compound 3b in the presence or absence of antioxidants (N-acetylcysteine, NAC or glutathione reduced ethyl ester, cell permeable glutathione, GSH). WebAll compounds were dissolved in 100% DMSO as 10-mM stock solutions and stored under nitrogen before use in all sub-sequent experiments. Manual dilution series To initiate the compound dilution series, we diluted the com-pound stock solution in culture media to a final concentration of 3 µM. This solution was further serially diluted to generate a how to style short natural nigerian hair